The underlying cause of the disease should be treated if possible. The medical treatment of choice is the synthetic vasopressin analogue - desmopressin. Desmopressin can be given nasally (10-20µg/day), orally (200µg/3x/day) or intramuscularly (2-4µg/day).
There are alternative medications such as chlorpropamide and carbamazepine that act by sensitising the renal tubules. Desmopressin is preferred as it is associated with less side effects and is more effective.